prednisolone

Ligand id: 2866

Name: prednisolone

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: prednisolone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 94.83
Molecular weight 360.19
XLogP 1.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1955))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
535 prednisolone
Synonyms
DELTA.1-Cortisol | Orapred® | Pediapred®
Comments
Prednisolone is a synthetic glucocorticoid. Marketed formulations may contain prednisolone sodium phosphate, prednisolone acetate, prednisolone hexanoate or prednisolone.
Database Links
BindingDB Ligand 19190
CAS Registry No. 50-24-8 (source: Scifinder)
ChEBI CHEBI:8378
ChEMBL Ligand CHEMBL131
DrugBank Ligand DB00860
GtoPdb PubChem SID 135650850
Immunopaedia Search prednisolone
NURSA Ligand 10.1621/W5MHAZ4ZDP
PubChem CID 5755
Search Google for chemical match using the InChIKey OIGNJSKKLXVSLS-VWUMJDOOSA-N
Search Google for chemicals with the same backbone OIGNJSKKLXVSLS
Search PubMed clinical trials prednisolone
Search PubMed titles prednisolone
Search PubMed titles/abstracts prednisolone
Search UniChem for chemical match using the InChIKey OIGNJSKKLXVSLS-VWUMJDOOSA-N
Search UniChem for chemicals with the same backbone OIGNJSKKLXVSLS
Wikipedia Prednisolone