fludrocortisone

Ligand id: 2873

Name: fludrocortisone

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 94.83
Molecular weight 380.2
XLogP 0.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1955), UK (2015))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
460 fludrocortisone
Synonyms
9α-Flourocortisol | Florinef®
Comments
Fludrocortisone is a synthetic mineralocorticoid drug.
Database Links
CAS Registry No. 127-31-1 (source: Scifinder)
ChEMBL Ligand CHEMBL1201388
DrugBank Ligand DB00687
GtoPdb PubChem SID 135650268
NURSA Ligand 10.1621/95N9YJPTF3
PubChem CID 31378
RCSB PDB Ligand ZK5
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Wikipedia Fludrocortisone