pilocarpine

Ligand id: 305

Name: pilocarpine

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 44.12
Molecular weight 208.12
XLogP 1.08
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1974))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
(3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one
Synonyms
pilocarpine hydrochloride | pilocarpine nitrate | pilokarpin | Salagen®
Comments
Pilocarpine is a parasympathomimetic alkaloid type cholinergic drug, exerting its clinical effects via activation of muscarinic acetylcholine M3 receptors.
Database Links
BindingDB Ligand 50008072
CAS Registry No. 92-13-7
ChEBI CHEBI:8207
ChEMBL Ligand CHEMBL550
DrugBank Ligand DB01085
GtoPdb PubChem SID 135650824
PubChem CID 5910
RCSB PDB Ligand 9PL
Search Google for chemical match using the InChIKey QCHFTSOMWOSFHM-WPRPVWTQSA-N
Search Google for chemicals with the same backbone QCHFTSOMWOSFHM
Search UniChem for chemical match using the InChIKey QCHFTSOMWOSFHM-WPRPVWTQSA-N
Search UniChem for chemicals with the same backbone QCHFTSOMWOSFHM
Wikipedia Pilocarpine