Ligand id: 3308
Name: cinacalcet
View more information in the IUPHAR Pharmacology Education Project: cinacalcet
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Molecular properties generated using the CDK |
Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (EMA & FDA (2004)) |
IUPAC Name ![]() |
N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine |
International Nonproprietary Names ![]() |
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INN number | INN |
8287 | cinacalcet |
Synonyms ![]() |
AMG-073 | Mimpara® | Sensipar® |
Comments |
Cinacalcet is a positive allosteric activator of the calcium-sensing receptor (CaSR), thus improving the effect of calcium on tissues expressing this receptor. |
Database Links ![]() |
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CAS Registry No. | 226256-56-0 (source: Scifinder) |
ChEMBL Ligand | CHEMBL1201284 |
DrugBank Ligand | DB01012 |
GtoPdb PubChem SID | 178100343 |
PubChem CID | 156419 |
Search Google for chemical match using the InChIKey | VDHAWDNDOKGFTD-MRXNPFEDSA-N |
Search Google for chemicals with the same backbone | VDHAWDNDOKGFTD |
Search PubMed clinical trials | cinacalcet |
Search PubMed titles | cinacalcet |
Search PubMed titles/abstracts | cinacalcet |
Search UniChem for chemical match using the InChIKey | VDHAWDNDOKGFTD-MRXNPFEDSA-N |
Search UniChem for chemicals with the same backbone | VDHAWDNDOKGFTD |
Wikipedia | Cinacalcet |