Synonyms: 3,4-dihydroxy-L-phenylalanine | Inbrija® (levodopa inhalation powder) | L-DOPA | Sinemet®
levodopa is an approved drug (FDA (1993), EMA (2003))
Compound class:
Metabolite
Comment: L-DOPA is the precursor to the neurotransmitters dopamine collectively known as catecholamines. Used in the treatment of Parkisons disease. Note a deuterated derivative D3 L-DOPA with enhanced properties is under development.
View more information in the IUPHAR Pharmacology Education Project: levodopa |
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Classification | |
Compound class | Metabolite |
Approved drug? | Yes (FDA (1993), EMA (2003)) |
WHO Essential Medicine | WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version. Click to view more information about the WHO Model Lists of Essential Medicines. |
Prodrug | foslevodopa |
IUPAC Name |
(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid |
International Nonproprietary Names | |
INN number | INN |
2651 | levodopa |
Synonyms |
3,4-dihydroxy-L-phenylalanine | Inbrija® (levodopa inhalation powder) | L-DOPA | Sinemet® |
Database Links | |
CAS Registry No. | 59-92-7 (source: Scifinder) |
ChEBI | CHEBI:15765 |
ChEMBL Ligand | CHEMBL1009 |
DrugBank Ligand | DB01235 |
DrugCentral Ligand | 1567 |
GtoPdb PubChem SID | 178100545 |
PubChem CID | 6047 |
RCSB PDB Ligand | DAH |
Search Google for chemical match using the InChIKey | WTDRDQBEARUVNC-LURJTMIESA-N |
Search Google for chemicals with the same backbone | WTDRDQBEARUVNC |
Search PubMed clinical trials | levodopa |
Search PubMed titles | levodopa |
Search PubMed titles/abstracts | levodopa |
UniChem Compound Search for chemical match using the InChIKey | WTDRDQBEARUVNC-LURJTMIESA-N |
UniChem Connectivity Search for chemical match using the InChIKey | WTDRDQBEARUVNC-LURJTMIESA-N |
Wikipedia | L-DOPA |