Synonyms: BA-679-BR | Spiriva®
tiotropium is an approved drug (FDA (2004))
Compound class:
Synthetic organic
Comment: We have chosen to display the structure of the parent compound, tiotropium, as this reflects the compound used in the experimental data listed under the 'biological activity' tab, and the links in the table above also represent the parent compound. However, the INN-assigned compound is in complex with bromide, the approved drug is also administered in this preparation. Note that the activity data in PubChem for this compound is split between the parent and the preparation with bromide.
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖![]() View more information in the IUPHAR Pharmacology Education Project: tiotropium |
|
Classification ![]() |
|
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (2004)) |
WHO Essential Medicine | WHO Model List of Essential Medicines (21st List, 2019). Access PDF version. |
IUPAC Name ![]() |
(1R,2R,4S,5S)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0^{2,4}]nonan-9-ium |
International Nonproprietary Names ![]() |
|
INN number | INN |
6965 | tiotropium bromide |
Synonyms ![]() |
BA-679-BR | Spiriva® |
Database Links ![]() |
|
CAS Registry No. | 186691-13-4 |
ChEMBL Ligand | CHEMBL3305968 |
DrugBank Ligand | DB01409 |
GtoPdb PubChem SID | 135651266 |
PubChem CID | 5487427 |
Search Google for chemical match using the InChIKey | LERNTVKEWCAPOY-FPISHFTHSA-N |
Search Google for chemicals with the same backbone | LERNTVKEWCAPOY |
Search PubMed clinical trials | tiotropium bromide |
Search PubMed titles | tiotropium bromide |
Search PubMed titles/abstracts | tiotropium bromide |
Search UniChem for chemical match using the InChIKey | LERNTVKEWCAPOY-FPISHFTHSA-N |
Search UniChem for chemicals with the same backbone | LERNTVKEWCAPOY |
SynPHARM | 82388 (in complex with M1 receptor) |
Wikipedia | Tiotropium_bromide |