GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

INSL5 (A chain)   Click here for help

GtoPdb Ligand ID: 3752

Synonyms: insulin-like peptide 5 (A chain)
Compound class: Endogenous peptide in human, mouse or rat
Species: Human
Is a component of
INSL5
Peptide Sequence Click here for help
XDLQTLCCTDGCSMTDLSALC
pGlu-Asp-Leu-Gln-Thr-Leu-Cys-Cys-Thr-Asp-Gly-Cys-Ser-Met-Thr-Asp-Leu-Ser-Ala-Leu-Cys
Post-translational Modification
The N-terminal glutamine is cyclised into pyroglutamate (represented by pGlu and X).

Fully active INSL5 is a heterodimer of the B chain and the A chain linked by two disulfide bonds, the first between B chain (residue 29) and A chain (residue 122), and the second between B chain (residue 41) and A chain (residue 135).