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                                                                Synonyms: Thyrogen® | thyroid-stimulating hormone | thyrotropin
                                 
                                                         
                            
                            
                            
                                 
                                
                                TSH is an approved drug (FDA (1953)) 
                                                        
                                                    
                                Compound class: 
                                                            Endogenous peptide in human, mouse or rat
                                 
                                
                                    
                                        Comment: The drug thyrotropin alfa is a peptide heterodimer consisting of an α and β subunit and mimics the endogenous peptide hormone.
                                    
                                 
                            
                                
                                    Species: Human
                                 
                            
                            
                          
                                
                                    
                                
                          
                                View more information in the IUPHAR Pharmacology Education Project: tsh  | 
                                    
| Subunits | 
| TSH β subunit | 
| glycoprotein hormone common alpha subunit | 
Peptide Sequence ![]()  | 
                                                                
| No information available. | 
| Post-translational Modification | |
| The production of biologically active TSH requires appropriately folded TSHβ and common α subunits that assemble to form the TSH heterodimer. | |