succinylcholine   

GtoPdb Ligand ID: 4004

Synonyms: Quelicin® | suxamethonium
succinylcholine is an approved drug (FDA (1952))
Compound class: Synthetic organic
Comment: Succinylcholine (sux) is a short-acting depolarizing neuromuscular blocker. It acts as an acetylcholine agonist at nicotinic acetylcholine receptors at neuromuscular junctions, resulting in persistent depolarization of the motor end plate.
2D Structure
Click here for structure editor
Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 11
Topological polar surface area 52.6
Molecular weight 290.22
XLogP -0.74
No. Lipinski's rules broken 1
SMILES / InChI / InChIKey
Canonical SMILES O=C(OCC[N+](C)(C)C)CCC(=O)OCC[N+](C)(C)C
Isomeric SMILES O=C(OCC[N+](C)(C)C)CCC(=O)OCC[N+](C)(C)C
InChI InChI=1S/C14H30N2O4/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6/h7-12H2,1-6H3/q+2
InChI Key AXOIZCJOOAYSMI-UHFFFAOYSA-N
Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1952))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
trimethyl[2-({4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl}oxy)ethyl]azanium
International Nonproprietary Names
INN number INN
26 suxamethonium chloride
Synonyms
Quelicin® | suxamethonium
Database Links
CAS Registry No. 306-40-1 (source: Scifinder)
ChEMBL Ligand CHEMBL703
DrugBank Ligand DB00202
DrugCentral Ligand 2489
GtoPdb PubChem SID 178100830
PubChem CID 5314
RCSB PDB Ligand SCK
Search Google for chemical match using the InChIKey AXOIZCJOOAYSMI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone AXOIZCJOOAYSMI
Search PubMed clinical trials suxamethonium chloride
Search PubMed titles suxamethonium chloride
Search PubMed titles/abstracts suxamethonium chloride
Search UniChem for chemical match using the InChIKey AXOIZCJOOAYSMI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone AXOIZCJOOAYSMI
Wikipedia Suxamethonium_chloride