felodipine   Click here for help

GtoPdb Ligand ID: 4190

Synonyms: Plandil® | Renedil®
Approved drug
felodipine is an approved drug (FDA (1991))
Compound class: Synthetic organic
Comment: Felodipine is a long-acting calcium channel blocker, and one of the dihydropyridine class of drugs.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 64.63
Molecular weight 383.07
XLogP 5.08
No. Lipinski's rules broken 1
SMILES / InChI / InChIKey
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Canonical SMILES CCOC(=O)C1=C(C)NC(=C(C1c1cccc(c1Cl)Cl)C(=O)OC)C
Isomeric SMILES CCOC(=O)C1=C(C)NC(=C(C1c1cccc(c1Cl)Cl)C(=O)OC)C
InChI InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
InChI Key RZTAMFZIAATZDJ-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1991))
IUPAC Name Click here for help
3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
International Nonproprietary Names Click here for help
INN number INN
4877 felodipine
Synonyms Click here for help
Plandil® | Renedil®
Database Links Click here for help
CAS Registry No. 72509-76-3 (source: Scifinder)
ChEMBL Ligand CHEMBL1480
DrugBank Ligand DB01023
DrugCentral Ligand 1142
GtoPdb PubChem SID 178101007
PubChem CID 3333
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Wikipedia Felodipine

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Tocris
Felodipine
Cat. No. 2960