S18986   

GtoPdb Ligand ID: 4304

Synonyms: S 18986 | S-18986
Compound class: Synthetic organic
Comment: S18968 is a positive allosteric modulator of AMPA-type glutamate receptors (an AMPA potentiator), with potential cognition-enhancing properties [1-2]. S18986 corresponds to the S enantiomer.
2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 57.79
Molecular weight 224.06
XLogP 1.67
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES O=S1(=O)NC2CCCN2c2c1cccc2
Isomeric SMILES O=S1(=O)N[C@H]2CCCN2c2c1cccc2
InChI InChI=1S/C10H12N2O2S/c13-15(14)9-5-2-1-4-8(9)12-7-3-6-10(12)11-15/h1-2,4-5,10-11H,3,6-7H2/t10-/m1/s1
InChI Key MNTIJYGEITVWHU-SNVBAGLBSA-N
Classification
Compound class Synthetic organic
IUPAC Name
(6S)-8$l^{6}-thia-2,7-diazatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-triene-8,8-dione
Synonyms
S 18986 | S-18986
Database Links
CAS Registry No. 175340-20-2 (source: Scifinder)
ChEMBL Ligand CHEMBL320642
GtoPdb PubChem SID 178101121
PubChem CID 637863
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Wikipedia S-18986

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Tocris
S 18986
Cat. No. 3911