SB202190   Click here for help

GtoPdb Ligand ID: 4307

Synonyms: SB 202190 | SB-202190
PDB Ligand Immunopharmacology Ligand
Compound class: Synthetic organic
Comment: SB202190 is a potent and selective p38 MAPK inhibitor, that preferentially inhibits p38α and p38β.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 61.8
Molecular weight 331.11
XLogP 4.63
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES Oc1ccc(cc1)c1nc(c([nH]1)c1ccc(cc1)F)c1ccncc1
Isomeric SMILES Oc1ccc(cc1)c1nc(c([nH]1)c1ccc(cc1)F)c1ccncc1
InChI InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)
InChI Key QHKYPYXTTXKZST-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol
Synonyms Click here for help
SB 202190 | SB-202190
Database Links Click here for help
CAS Registry No. 152121-30-7 (source: Scifinder)
ChEMBL Ligand CHEMBL278041
GtoPdb PubChem SID 178101124
PubChem CID 5353940
RCSB PDB Ligand 2RE
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