CXCL12α   Click here for help

GtoPdb Ligand ID: 4358

Synonyms: CXCL12 α | SDF-1α | stromal cell-derived factor-1α
Immunopharmacology Ligand
Comment: CXCL12-1α and β were the first isoforms of this chemokine identified. Both proteins contain a signal peptide sequence that mediates their secretion via the canonical intracellular secretory pathway. CXCL12 participates in a variety of processes central to homeostasis and physiology, exerting its biological effects by binding to the chemokine receptors CXCR4 and CXCR7.
Species: Human
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Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Chemokines
Synonyms Click here for help
CXCL12 α | SDF-1α | stromal cell-derived factor-1α
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
CXCL12 C-X-C motif chemokine ligand 12 Human chemokine (C-X-C motif) ligand 12 chemokine (C-X-C motif) ligand 12, PBSF, SCYB12, SDF1, SDF-1a, SDF1A, SDF-1b, SDF1B, stromal cell-derived factor 1, TLSF-a, TLSF-b, TPAR1
Database Links Click here for help
Ensembl Gene ENSG00000107562 (Hs)
Entrez Gene 6387
GtoPdb PubChem SID 135651881
Human Protein Atlas ENSG00000107562 (Hs)
Immunopaedia Search CXCL12α
UniProtKB P48061 (Hs)
Wikipedia Stromal_cell-derived_factor-1