GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

thrombin   Click here for help

GtoPdb Ligand ID: 4453

Compound class: Endogenous peptide in human, mouse or rat
Comment: Thrombin is a serine protease that acts as an agonist at the protease-activated GPCR family. Active thrombin is a complex between thrombin light chain and thrombin heavy chain. The chains are linked by a disulphide bond between cysteine residues at position 9 of the light chain and 118 of the heavy chain.
Species: Human

This ligand is also described as a target entry: coagulation factor II, thrombin

Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Database Links Click here for help
Specialist databases
GPCRdb Ligand thrombin
Other databases
CAS Registry No. 9002-04-4 (source: Scifinder)
CATH/Gene3D 4.10.740.10, 4.10.140.10
DrugBank Target P00734 (Hs)
Ensembl Gene ENSG00000180210 (Hs)
GtoPdb PubChem SID 135651891
Human Protein Atlas ENSG00000180210 (Hs)
UniProtKB P00734 (Hs)
Wikipedia Thrombin