mazindol   

GtoPdb Ligand ID: 4797

Synonyms: Mazanor® | Sanorex®
mazindol is an approved drug (FDA (1973))
Compound class: Synthetic organic
Comment: Mazindol is a tetracyclic chemical, with anorectic, appetite suppressing action. Pharmacologically it acts as a sympathomimetic amine (like amphetamine).
2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 35.83
Molecular weight 284.07
XLogP 3.77
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES Clc1ccc(cc1)C1(O)c2ccccc2C2=NCCN12
Isomeric SMILES Clc1ccc(cc1)C1(O)c2ccccc2C2=NCCN12
InChI InChI=1S/C16H13ClN2O/c17-12-7-5-11(6-8-12)16(20)14-4-2-1-3-13(14)15-18-9-10-19(15)16/h1-8,20H,9-10H2
InChI Key ZPXSCAKFGYXMGA-UHFFFAOYSA-N
Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1973))
IUPAC Name
5-(4-chlorophenyl)-2H,3H,5H-imidazo[2,1-a]isoindol-5-ol
International Nonproprietary Names
INN number INN
2895 mazindol
Synonyms
Mazanor® | Sanorex®
Database Links
CAS Registry No. 22232-71-9 (source: Scifinder)
ChEMBL Ligand CHEMBL781
DrugBank Ligand DB00579
DrugCentral Ligand 1640
GtoPdb PubChem SID 178101499
PubChem CID 4020
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