Synonyms: 5-fluoro-2'-deoxyuridine | floxidine | FUDR®
floxuridine is an approved drug (FDA (1970))
Compound class:
Synthetic organic
Comment: Floxuridine is metabolized to 5-fluorouracil when given by rapid injection, but is converted to floxuridine monophosphate when given as continuous infusion. 5-fluorouracil is considered the active drug.
|
|
Classification ![]() |
|
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1970)) |
Approved drug? | Yes. FDA (1970) |
Is prodrug? | Yes |
Active form | 5-fluorouracil |
IUPAC Name ![]() |
5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione |
International Nonproprietary Names ![]() |
|
INN number | INN |
2010 | floxuridine |
Synonyms ![]() |
5-fluoro-2'-deoxyuridine | floxidine | FUDR® |
Database Links ![]() |
|
CAS Registry No. | 50-91-9 (source: Scifinder) |
ChEMBL Ligand | CHEMBL917 |
DrugBank Ligand | DB00322 |
DrugCentral Ligand | 1184 |
GtoPdb PubChem SID | 178101503 |
PubChem CID | 5790 |
Search Google for chemical match using the InChIKey | ODKNJVUHOIMIIZ-RRKCRQDMSA-N |
Search Google for chemicals with the same backbone | ODKNJVUHOIMIIZ |
Search PubMed clinical trials | floxuridine |
Search PubMed titles | floxuridine |
Search PubMed titles/abstracts | floxuridine |
UniChem Compound Search for chemical match using the InChIKey | ODKNJVUHOIMIIZ-RRKCRQDMSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | ODKNJVUHOIMIIZ-RRKCRQDMSA-N |
Wikipedia | Floxuridine |
Product supplier links are provided as a service to assist in identifying commercial suppliers of reagents that are mentioned on the IUPHAR/BPS Guide to PHARMACOLOGY database website, and do not imply their endorsement by NC-IUPHAR.
Links are provided in return for sponsorship, used to fund improvements to this database. The sponsorship account is managed and audited by the University of Edinburgh, a charitable body registered in Scotland, SC005336. If you are interested in sponsoring the database, please contact us.
✖
Floxuridine (links to external site)
Cat. No. HY-B0097 |