Classification
Compound class	Endogenous peptide in human, mouse or rat
Approved drug?	Yes (FDA (1976), EMA (2001))

International Nonproprietary Names
INN number	INN
239	somatropin

Synonyms

NutropinAq® | Omnitrope® | Saizen® | somatotropin

Comments

Human growth hormone 1 (somatropin) produced by recombinant technology is an approved drug with the INN somatropin. This has identical 191-amino acid sequence to the endogenous hormone. Biosimilar drug: The EMA approved the biosimilar named Omnitrope (Sandoz GmbH) in 2006.

Gene/Precursor

Gene symbol Gene name Species Precursor protein name Synonyms GH1 growth hormone 1 Human prepro-growth hormone 1 GH, GHN, GH-N, hGH-N, pituitary growth hormone

Database Links
CAS Registry No.	12629-01-5 (source: Scifinder)
DrugBank Ligand	DB00052 (Hs)
Ensembl Gene	ENSG00000189162 (Hs)
GtoPdb PubChem SID	178101641
Human Protein Atlas	ENSG00000189162 (Hs)
Search PubMed clinical trials	somatropin
Search PubMed titles	somatropin
Search PubMed titles/abstracts	somatropin
UniProtKB	P01241 (Hs)
Wikipedia	Growth_hormone_1