IFN-α2   Click here for help

GtoPdb Ligand ID: 4960

Synonyms: IFN-alpha-2 | interferon alpha-2 | Roferon A®
Approved drug Immunopharmacology Ligand
IFN-α2 is an approved drug (FDA (1989))
Comment: IFN-α2 is a type I IFN. The sequence of the recombinant peptide used clinically and known as interferon alfa-2a, is identical to that of human IFN-α2. Interferon alfa-2a has anti-viral, immunomodulatory and antineoplastic actions.
Pegylated IFN alfa 2a is on the World Health Organization's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interferons
Approved drug? Yes (FDA (1989))
Synonyms Click here for help
IFN-alpha-2 | interferon alpha-2 | Roferon A®
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
IFNA2 interferon alpha 2 Human prepro-interferon alpha-2 alpha-2a interferon, IFNA, IFN-alphaA, interferon, alpha 2, interferon alpha 2b, interferon alpha A
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 624
Other databases
Ensembl Gene ENSG00000188379 (Hs)
GtoPdb PubChem SID 178101658
Human Protein Atlas ENSG00000188379 (Hs)
UniProtKB P01563 (Hs)
Wikipedia IFNA2