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                                                                Synonyms: IFN-alpha-8 | interferon alpha-8 | interferon alpha-B | interferon alpha-B2
                                 
                                                         
                            
                            
                            
                                Compound class: 
                                                            Endogenous peptide in human, mouse or rat
                                 
                                
                                    
                                        Comment: IFN-α8 is a type I IFN.
                                    
                                 
                            
                                
                                    Species: Human
                                 
                            
                            
                          
                                
                                    
                                
                          
                                   
                                   
                                  
                                    
                                    
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| Immunopharmacology Comments | 
| IFN-α8 binds the IFN-α/β receptor (IFNAR), a dimeric receptor that consists of protein chains encoded by the IFNAR1 and IFNAR2 genes, and induces expression of proteins containing ISRE or GAS transcription elements. |