IL-24

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Ligands
IL-24 (Human)

GtoPdb Ligand ID: 4990

Synonyms: interleukin-24 | MDA-7 | melanoma differentiation-associated gene 7 protein

Compound class: Endogenous peptide in human, mouse or rat

Comment: IL-24 is an IL-10 related type II cytokine.

Species: Human

Summary
Biological activity
References
Structure
Immunopharmacology

Immunopharmacology Comments
IL-24 is produced by monocytes, Th2 cells and melanocytes [1]. It stimulates the JAK/STAT signalling pathway via interaction with the IL-20 or IL-22 receptors. It is involved in inflammation and epidermal cell function and has proapoptotic activity.

Immunopharmacology Comments

IL-24 is produced by monocytes, Th2 cells and melanocytes [1]. It stimulates the JAK/STAT signalling pathway via interaction with the IL-20 or IL-22 receptors. It is involved in inflammation and epidermal cell function and has proapoptotic activity.