leptin   Click here for help

GtoPdb Ligand ID: 5015

Compound class: Endogenous peptide in human, mouse or rat
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species

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View more information in the IUPHAR Pharmacology Education Project: leptin

Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
LEP leptin Human prepro-leptin leptin (murine obesity homolog), leptin (obesity homolog, mouse), OB, OBS
Database Links Click here for help
Ensembl Gene ENSG00000174697 (Hs)
GtoPdb PubChem SID 178101712
Human Protein Atlas ENSG00000174697 (Hs)
UniProtKB P41159 (Hs)
Wikipedia Leptin