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chromogranin A   Click here for help

GtoPdb Ligand ID: 5165

Synonyms: CgA | pituitary secretory protein I | SP-1
Compound class: Endogenous peptide in human, mouse or rat
Species: Human
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View more information in the IUPHAR Pharmacology Education Project: chromogranin a

Peptide Sequence Click here for help
LPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQECFETLRGDERILSILRHQNLLKELQDLALQGAKERAHQQKKHS
GFEDELSEVLENQSSQAELKEAVEEPSSKDVMEKREDSKEAEKSGEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEE
EATNTHPPASLPSQKYPGPQAEGDSEGLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEEAVPEEEGPTVVLNPHP
SLGYKEIRKGESRSEALAVDGAGKPGAEEAQDPEGKGEQEHSQQKEEEEEMAVVPQGLFRGGKSGELEQEEERLSKEWED
SKRWSKMDQLAKELTAEKRLEGQEEEEDNRDSSMKLSFRARAYGFRGPGPQLRRGWRPSSREDSLEAGLPLQVRGYPEEK
KEEEGSANRRPEDQELESLSAIEAELEKVAHQLQALRRG
Post-translational Modification
Serine resdiues at positions 94, 95, 118, 124, 185, 200, 252, 282, 304, 315 and 384 are phosphorylated to phosphoserine; threonine resdiues at positions 163, 165 and 233 undergo O-linked glycosylation; glycine residue at position 301 and arginine at position 438 undergo amidation