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β-catenin   Click here for help

GtoPdb Ligand ID: 5371

Synonyms: catenin beta-1
Compound class: Endogenous peptide in human, mouse or rat
Species: Human
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
transcription factor 4 Ligand is endogenous in the given species Hs None Binding - - - 1
⤷ Formation of the beta-catenin/TCF4 transcription complex [1]
Other ligands which bind to or alter the activity of this ligand
Key to terms and symbols Click column headers to sort
Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
compound 41 [PMID: 36630177] Small molecule or natural product Hs None Binding 6.6 pKd - 3
⤷ pKd 6.6 (Kd 2.6x10-7 M) [3]
Description: Binding affinity for β-catenin determined by SPR assay
zolucatetide Peptide Hs Inhibitor Binding:
Protein-protein interaction inhibitor for β-catenin/TCF4 binding		 >7.3 pIC50 - 2
⤷ pIC50 >7.3 (IC50 <5x10-8 M) Protein-protein interaction inhibitor for β-catenin/TCF4 binding [2]
Ligand mentioned in the following text fields
Class Frizzled GPCRs overview