IL-17C   Click here for help

GtoPdb Ligand ID: 5875

Synonyms: cytokine CX2 | interleukin-17C
Immunopharmacology Ligand
Comment: IL-17C is an IL-17 homolog, secreted by epithelial cells in response to bacterial challenge and inflammatory stimuli and that acts in an autocrine manner to control the innate epithelial immune responses necessary for regulating intestinal inflammation and barrier function [1-2].
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interleukins
Synonyms Click here for help
cytokine CX2 | interleukin-17C
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
IL17C interleukin 17C Human prepro-interleukin-17C CX2, IL-17C, IL-21, MGC126884, MGC138401
Database Links Click here for help
CATH/Gene3D 2.10.90.10
Ensembl Gene ENSG00000124391 (Hs)
GtoPdb PubChem SID 178102499
Human Protein Atlas ENSG00000124391 (Hs)
UniProtKB Q9P0M4 (Hs)