methazolamide   Click here for help

GtoPdb Ligand ID: 6828

Synonyms: methenamide | Neptazane®
Approved drug
methazolamide is an approved drug (FDA (1959))
Compound class: Synthetic organic
Comment: Inhibits carbonic anhydrases. This compound is also represented on ChEMBL by the entry with ID CHEMBL19.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 144.03
Molecular weight 236
XLogP -0.98
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES CC(=O)N=c1sc(nn1C)S(=O)(=O)N
Isomeric SMILES CC(=O)N=c1sc(nn1C)S(=O)(=O)N
InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)
InChI Key FLOSMHQXBMRNHR-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1959))
IUPAC Name Click here for help
N-(3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene)acetamide
International Nonproprietary Names Click here for help
INN number INN
882 methazolamide
Synonyms Click here for help
methenamide | Neptazane®
Database Links Click here for help
CAS Registry No. 554-57-4
ChEMBL Ligand CHEMBL1335656
DrugBank Ligand DB00703
DrugCentral Ligand 1741
GtoPdb PubChem SID 178103434
PubChem CID 4100
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SynPHARM 78861 (in complex with carbonic anhydrase 1)
Wikipedia Methazolamide