amlodipine

Ligand id: 6981

Name: amlodipine

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 99.88
Molecular weight 408.15
XLogP 3.16
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1992), EMA (2007))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
O3-ethyl O5-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
International Nonproprietary Names
INN number INN
5729 amlodipine
Synonyms
amlodipine besylate | amlodipine maleate | Copalia® (amlodipine + valsartan) | Katerzia® (amlodipine oral suspension, 1 mg/mL) | Norvasc® | UK-4834011
Comments
Amlodipine is a long-acting dihydropyridine class calcium channel blocker.
Amlodipine is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Database Links
CAS Registry No. 88150-42-9 (source: Scifinder)
ChEMBL Ligand CHEMBL1491
DrugBank Ligand DB00381
GtoPdb PubChem SID 178103560
PubChem CID 2162
Search Google for chemical match using the InChIKey HTIQEAQVCYTUBX-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HTIQEAQVCYTUBX
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Search UniChem for chemical match using the InChIKey HTIQEAQVCYTUBX-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone HTIQEAQVCYTUBX
Wikipedia Amlodipine