fluocinolone acetonide   Click here for help

GtoPdb Ligand ID: 7077

Synonyms: Capex® | Iluvien® | Synalar®
Approved drug Immunopharmacology Ligand
fluocinolone acetonide is an approved drug (FDA (1963))
Compound class: Synthetic organic
Comment: Fluocinolone acetonide is a corticosteroid.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 93.06
Molecular weight 452.2
XLogP 1.15
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES OCC(=O)C12OC(OC1CC1C2(C)CC(O)C2(C1CC(C1=CC(=O)C=CC21C)F)F)(C)C
Isomeric SMILES OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1C[C@@H](C1=CC(=O)C=C[C@]21C)F)F)(C)C
InChI InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
InChI Key FEBLZLNTKCEFIT-VSXGLTOVSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1963))
International Nonproprietary Names Click here for help
INN number INN
1046 fluocinolone acetonide
Synonyms Click here for help
Capex® | Iluvien® | Synalar®
Database Links Click here for help
CAS Registry No. 67-73-2
ChEMBL Ligand CHEMBL989
DrugBank Ligand DB00591
DrugCentral Ligand 1204
GtoPdb PubChem SID 178103656
PubChem CID 6215
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Wikipedia Fluocinolone acetonide