loratadine

Ligand id: 7216

Name: loratadine

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: loratadine

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 42.43
Molecular weight 382.14
XLogP 3.82
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1993))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate
International Nonproprietary Names
INN number INN
5864 loratadine
Synonyms
Claritin® | SCH-29851
Comments
Loratidine is an antihistamine; peripheral H1 receptor antagonist; antiallergic agent.
Database Links
CAS Registry No. 79794-75-5
ChEMBL Ligand CHEMBL998
DrugBank Ligand DB00455
GtoPdb PubChem SID 178103791
PubChem CID 3957
Search Google for chemical match using the InChIKey JCCNYMKQOSZNPW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JCCNYMKQOSZNPW
Search PubMed clinical trials loratadine
Search PubMed titles loratadine
Search PubMed titles/abstracts loratadine
Search UniChem for chemical match using the InChIKey JCCNYMKQOSZNPW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone JCCNYMKQOSZNPW
Wikipedia Loratidine

Product suppliers

View disclaimer

Tocris
Loratidine
Cat. No. 1944