florbetapir   Click here for help

GtoPdb Ligand ID: 7344

Synonyms: AMYViD® | AV-45 | florbetapir (18F)
Approved drug  Ligand is labelled  Ligand is radioactive
florbetapir is an approved drug (FDA (2012), EMA (2013))
Compound class: Synthetic organic
Comment: Florbetapir F18 is a molecular imaging agent (diagnostic radiopharmaceutical) that binds to β-amyloid aggregates in Alzheimer's brains.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 12
Topological polar surface area 52.61
Molecular weight 360.18
XLogP 3.73
No. Lipinski's rules broken 1
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Canonical SMILES FCCOCCOCCOc1ccc(cn1)C=Cc1ccc(cc1)NC
Isomeric SMILES [18F]CCOCCOCCOc1ccc(cn1)/C=C/c1ccc(cc1)NC
InChI InChI=1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+/i21-1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2012), EMA (2013))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
9193 florbetapir (18F)
Synonyms Click here for help
AMYViD® | AV-45 | florbetapir (18F)
Database Links Click here for help
CAS Registry No. 956103-76-7 (source: SciFinder)
ChEMBL Ligand CHEMBL1774461
DrugCentral Ligand 4285
GtoPdb PubChem SID 178103916
PubChem CID 24822371
Search Google for chemical match using the InChIKey YNDIAUKFXKEXSV-CRYLGTRXSA-N
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UniChem Compound Search for chemical match using the InChIKey YNDIAUKFXKEXSV-CRYLGTRXSA-N
UniChem Connectivity Search for chemical match using the InChIKey YNDIAUKFXKEXSV-CRYLGTRXSA-N
Wikipedia Florbetapir