Classification
Compound class	Synthetic organic
Approved drug?	Yes (FDA (2017), EMA (2018))

IUPAC Name

N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine

International Nonproprietary Names
INN number	INN
10036	abemaciclib

Synonyms

CS-1230 | HY-16297A | LY 2835219 | LY2835219 | Verzenio® | Verzenios®

Comments

Abemaciclib (LY2835219) is a selective ATP-competitive inhibitor of the cyclin-dependent kinases CDK4 and CDK6 [6].

Database Links
CAS Registry No.	1231929-97-7 (source: Scifinder)
ChEMBL Ligand	CHEMBL3301610
GtoPdb PubChem SID	178103954
PubChem CID	46220502
RCSB PDB Ligand	6ZV
Search Google for chemical match using the InChIKey	UZWDCWONPYILKI-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey	UZWDCWONPYILKI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	UZWDCWONPYILKI