pegloticase   Click here for help

GtoPdb Ligand ID: 7463

Synonyms: Krystexxa® | puricase
Approved drug
pegloticase is an approved drug (FDA (2010), EMA (2013))
Comment: Pegloticase is a porcine-like recombinant uricase, which is PEGylated to increase its biological half-life. The peptide sequence for the enzyme monomer is available in the ChEMBL entry. The enzyme is a tetramer, and lysine residues are PEGylated.
Classification Click here for help
Compound class Peptide or derivative
Approved drug? Yes (FDA (2010), EMA (2013))
International Nonproprietary Names Click here for help
INN number INN
8934 pegloticase
Synonyms Click here for help
Krystexxa® | puricase
Database Links Click here for help
ChEMBL Ligand CHEMBL1237025
GtoPdb PubChem SID 187051766
Search PubMed clinical trials pegloticase
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Wikipedia Pegloticase