Synonyms: Krystexxa® | puricase
pegloticase is an approved drug (FDA (2010), EMA (2013))
Compound class:
Peptide or derivative
Comment: Pegloticase is a porcine-like recombinant uricase, which is PEGylated to increase its biological half-life. The peptide sequence for the enzyme monomer is available in the ChEMBL entry. The enzyme is a tetramer, and lysine residues are PEGylated.
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Classification | |
Compound class | Peptide or derivative |
Approved drug? | Yes (FDA (2010), EMA (2013)) |
International Nonproprietary Names | |
INN number | INN |
8934 | pegloticase |
Synonyms |
Krystexxa® | puricase |
Database Links | |
ChEMBL Ligand | CHEMBL1237025 |
GtoPdb PubChem SID | 187051766 |
Search PubMed clinical trials | pegloticase |
Search PubMed titles | pegloticase |
Search PubMed titles/abstracts | pegloticase |
Wikipedia | Pegloticase |