prasugrel   Click here for help

GtoPdb Ligand ID: 7562

Synonyms: CS-747 | Effient® | Efient®
Approved drug
prasugrel is an approved drug (FDA and EMA (2009))
Compound class: Synthetic organic
Comment: This drug is metabolised to its active metabolite R-138727.
Marketed formulations may contain prasugrel hydrochloride (PubChem CID 10158453).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 74.85
Molecular weight 373.11
XLogP 2.2
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES CC(=O)Oc1sc2c(c1)CN(CC2)C(c1ccccc1F)C(=O)C1CC1
Isomeric SMILES CC(=O)Oc1sc2c(c1)CN(CC2)C(c1ccccc1F)C(=O)C1CC1
InChI InChI=1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3
InChI Key DTGLZDAWLRGWQN-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA and EMA (2009))
Is prodrug? Yes
Active form R-138727
IUPAC Name Click here for help
[5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[4,5-c]pyridin-2-yl] acetate
International Nonproprietary Names Click here for help
INN number INN
8503 prasugrel
Synonyms Click here for help
CS-747 | Effient® | Efient®
Database Links Click here for help
CAS Registry No. 150322-43-3
ChEMBL Ligand CHEMBL1201772
DrugBank Ligand DB06209
DrugCentral Ligand 4113
GtoPdb PubChem SID 223365898
PubChem CID 6918456
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Wikipedia Prasugrel

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Tocris
Prasugrel
Cat. No. 6317