dupilumab   Click here for help

GtoPdb Ligand ID: 7574

Synonyms: Dupixent® | REGN668 | SAR231893
Approved drug Immunopharmacology Ligand
dupilumab is an approved drug (EMA & FDA (2017))
Compound class: Antibody
Comment: Dupilumab is fully human monoclonal antibody against the α subunit of the IL4 receptor.
Peptide sequences for this antibody are available from its IMGT/mAb-db record. Dupilumab was produced using Regeneron's genetically engineered VelocImmune® mice which have humanized immunoglobulin gene loci and produce human:mouse hybrid antibodies that can rapidly be converted to fully human antibodies [3].
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Classification Click here for help
Compound class Antibody
Approved drug? Yes (EMA & FDA (2017))
International Nonproprietary Names Click here for help
INN number INN
9669 dupilumab
Synonyms Click here for help
Dupixent® | REGN668 | SAR231893
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 449
Other databases
GtoPdb PubChem SID 223365910
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Wikipedia Dupilumab