florbetaben is an approved drug (EMA & FDA (2014))
Compound class:
Synthetic organic
Comment: Florbetaben F18 is the third PET (positron-emission tomography) reagent approved to identify amyloid-β (Aβ) as a diagnostic biomarker in the brains of patients with Alzheimer's disease (AD) [1]. Flutemetamol and florbetapir are the two other PET reagents approved for Aβ detection. These diagnostic tools allow direct and non-invasive in vivo visualisation and quantification of Aβ.
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
|
Classification ![]() |
|
Compound class | Synthetic organic |
Approved drug? | Yes (EMA & FDA (2014)) |
IUPAC Name ![]() |
4-[(E)-2-[4-[2-[2-(2-fluoranylethoxy)ethoxy]ethoxy]phenyl]ethenyl]-N-methylaniline |
International Nonproprietary Names ![]() |
|
INN number | INN |
9184 | florbetaben (18F) |
Synonyms ![]() |
|
[18F]BAY 94-9172 [1] | AV-1 [2] | BAY 94-9172 [2] | Neuraceq® |
Database Links ![]() |
|
CAS Registry No. | 902143-01-5 (source: Scifinder) |
DrugCentral Ligand | 4818 |
GtoPdb PubChem SID | 223366102 |
PubChem CID | 11501341 |
Search Google for chemical match using the InChIKey | NCWZOASIUQVOFA-FWZJPQCDSA-N |
Search Google for chemicals with the same backbone | NCWZOASIUQVOFA |
Search PubMed clinical trials | florbetaben |
Search PubMed titles | florbetaben |
Search PubMed titles/abstracts | florbetaben |
Search UniChem for chemical match using the InChIKey | NCWZOASIUQVOFA-FWZJPQCDSA-N |
Search UniChem for chemicals with the same backbone | NCWZOASIUQVOFA |
Wikipedia | Florbetaben_(18F) |