bavituximab   Click here for help

GtoPdb Ligand ID: 8002

Synonyms: Tarvacin ch3G4
Compound class: Antibody
Comment: Bavituximab is the first monoclonal antibody directed against phosphatidylserine, and is being investigated as a antineoplastic agent. Bavituximab belongs to an emerging class of antibodies known as vascular targeting agents (VTAs) which bind selectively to antigens present on tumour vascular cells. Typical VTAs either recruit host effector cells to destroy the tumour or are coupled to agents such as toxins, anticoagulants or pro-apoptotic drugs that occlude or destroy tumour blood vessels [3].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
8734 bavituximab
Synonyms Click here for help
Tarvacin ch3G4
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 149
Other databases
GtoPdb PubChem SID 249565682
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Wikipedia Bavituximab