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Synonyms: GROα | melanocyte growth-stimulatory activity | MIP-2
Compound class:
Endogenous peptide in human, mouse or rat
Comment: CXCL1 is a C-X-C motif chemokine expressed by macrophages, neutrophils and epithelial cells, that acts via the chemokine receptor CXCR2. CXCL1 is expressed by keratinocytes and endothelial cells at sites of epithelialization and neovascularization in the process of wound healing [2].
Species: Human
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
Classification  |
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| Compound class | Endogenous peptide in human, mouse or rat |
| Ligand families/groups | Chemokines |
| Synonyms |
| GROα | melanocyte growth-stimulatory activity | MIP-2 |
| Gene/Precursor |
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| Database Links |
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| Specialist databases | |
| GPCRdb Ligand | CXCL1 |
| Other databases | |
| Ensembl Gene | ENSG00000163739 (Hs) |
| Entrez Gene | 2919 |
| GtoPdb PubChem SID | 135651702 |
| Human Protein Atlas | ENSG00000163739 (Hs) |
| OMIM | 155730 |
| RefSeq Protein | NP_001502 |
| UniProtKB | P09341 (Hs) |
| Wikipedia | CXCL1 |
