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Synonyms: UNC 1999 | UNC-1999
Compound class: Synthetic organic
Comment: UNC1999 is a cell-permeable chemical probe for histone H3-lysine 27 (H3K27) methyltransferase EZH2 activity, developed by the Structural Genomics Consortium (SGC) in collaboration with the Center for Integrative Chemical Biology and Drug Discovery (CICBDD) at the University of North Carolina [1-2].
Click here to link to the SGC's full list of epigenetics probes.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Compound class||Synthetic organic|
|UNC 1999 | UNC-1999|
|CAS Registry No.||1431612-23-5 (source: Scifinder)|
|GtoPdb PubChem SID||249565917|
|Search Google for chemical match using the InChIKey||DPJNKUOXBZSZAI-UHFFFAOYSA-N|
|Search Google for chemicals with the same backbone||DPJNKUOXBZSZAI|
|Search UniChem for chemical match using the InChIKey||DPJNKUOXBZSZAI-UHFFFAOYSA-N|
|Search UniChem for chemicals with the same backbone||DPJNKUOXBZSZAI|
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Links are provided in return for sponsorship, used to fund improvements to this database. The sponsorship account is managed and audited by the University of Edinburgh, a charitable body registered in Scotland, SC005336. If you are interested in sponsoring the database, please contact us.✖
Cat. No. 4904