milatuzumab   Click here for help

GtoPdb Ligand ID: 8267

Synonyms: hLL1 | IMMU-115
Immunopharmacology Ligand
Compound class: Antibody
Comment: Milatuzumab is a humanized monoclonal antibody targeting CD74, a cell surface molecule which links the innate and adaptive immune responses by regulating the survival of macrophages and B cells. CD74 is also known as the invariant chain of major histocompatibility complex class II and acts as a receptor for macrophage migration inhibitory factor (MIF).
Milatuzumab may also be conjugated with doxorubicin creating the antibody-drug conjugate (ADC) hLL1-DOX (aka IMMU-110) [1].
Peptide sequence information for this antibody is available from its IMGT/mAb-DB link.
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
8922 milatuzumab
Synonyms Click here for help
hLL1 | IMMU-115
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 135
Other databases
GtoPdb PubChem SID 252166479
Search PubMed clinical trials milatuzumab
Search PubMed titles milatuzumab
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Wikipedia Milatuzumab