Synonyms: Rescula® (proposed trade name) | UF 021 | UF-021
unoprostone isopropyl is an approved drug (FDA (2000))
Compound class:
Synthetic organic
Comment: Note that the INN for this compound is for the carboxylic acid, whereas the compound used clinically is the isopropyl ester.
Unoprostone was originally developed as an intraocular pressure-reducing agent for use in glaucoma, however use for this indication has been discontinued. The focus is now on unoprostone's ability to treat retinal disease [3,5]. View more information in the IUPHAR Pharmacology Education Project: unoprostone isopropyl |
|
Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (2000)) |
Withdrawn drug? | Yes |
IUPAC Name |
propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoate |
International Nonproprietary Names | |
INN number | INN |
6920 | unoprostone |
Synonyms |
Rescula® (proposed trade name) | UF 021 | UF-021 |
Database Links | |
CAS Registry No. | 120373-24-2 (source: Scifinder) |
ChEBI | CHEBI:31731 |
ChEMBL Ligand | CHEMBL1200661 |
DrugCentral Ligand | 2794 |
GtoPdb PubChem SID | 252166494 |
PubChem CID | 5282175 |
Search Google for chemical match using the InChIKey | XXUPXHKCPIKWLR-JHUOEJJVSA-N |
Search Google for chemicals with the same backbone | XXUPXHKCPIKWLR |
Search PubMed clinical trials | unoprostone |
Search PubMed titles | unoprostone |
Search PubMed titles/abstracts | unoprostone |
UniChem Compound Search for chemical match using the InChIKey | XXUPXHKCPIKWLR-JHUOEJJVSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | XXUPXHKCPIKWLR-JHUOEJJVSA-N |