Bioactivity Comments

Peptide sequence match indicates that patents US7442778 [1] and US7138370 [5] cover this peptibody. Figure 15 in US7442778 gives an approximate concentration of 0.5nM peptibody to inhibit binding to human ang2 by 50%.

Selectivity at ligand targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference angiopoietin-2 Hs Antibody Binding 9.2 pKd - 5 ⤷ pKd 9.2 (Kd 6.7x10-10 M) [5]