fimepinostat

Ligand id: 8952

Name: fimepinostat

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 166.96
Molecular weight 508.16
XLogP 1.62
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Classification
Compound class Synthetic organic
IUPAC Name
N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide
International Nonproprietary Names
INN number INN
10504 fimepinostat
Synonyms
CUDC 907 | CUDC-907 | PI3K/HDAC Inhibitor centn
Comments
Fimepinostat (CUDC-907) is an investigational dual inhibitor of histone deacetylase (HDAC) and phosphatidylinositol 3-kinase (PI3K) activity [1]. The compound is orally available.
Database Links
CAS Registry No. 1339928-25-4 (source: PubChem)
GtoPdb PubChem SID 310264733
PubChem CID 54575456
Search Google for chemical match using the InChIKey JOWXJLIFIIOYMS-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JOWXJLIFIIOYMS
Search PubMed clinical trials fimepinostat
Search PubMed titles fimepinostat
Search PubMed titles/abstracts fimepinostat
Search UniChem for chemical match using the InChIKey JOWXJLIFIIOYMS-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone JOWXJLIFIIOYMS