Classification
Compound class	Antibody

International Nonproprietary Names
INN number	INN
9368	onartuzumab

Synonyms

MetMAb | OA-5D5 | OA5D5 | PRO 143966

Comments

Onartuzumab is an investigational, humanized monoclonal antibody targeting the MET receptor tyrosine kinase, a proto-oncogene which acts as a hepatocyte growth factor receptor. The protein is a monovalent (single-armed) construct, as opposed to bi-valent intact antibody structures. Peptide sequence information for this antibody is available from its IMGT/mAb-DB record. BLAST peptide analysis reveals identical match with sequences deposited with patent US7615529 [4], which relate to the monoclonal isolated from hybridoma 5D5.11.6 therein.

Database Links
Specialist databases
IMGT/mAb-DB	368
Other databases
GtoPdb PubChem SID	310264746
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