Compound class:
Endogenous peptide in human, mouse or rat
Comment: IL-34 is an endogenous ligand of the receptor tyrosine kinase, colony stimulating factor 1 receptor (CSF1R) [3]. It is a homodimeric cytokine.
Species: Human
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Immunopharmacology Comments |
IL-34 promotes the differentiation and viability of monocytes and macrophages via activation of the CSF1R. |