eldelumab   Click here for help

GtoPdb Ligand ID: 9047

Synonyms: BMS-936557 | MDX-1100
Immunopharmacology Ligand
Compound class: Antibody
Comment: Eldelumab (BMS-936557 and formerly MDX-1100) is a a fully human monoclonal antibody targeting the chemokine CXCL10 (a.k.a. interferon-γ-inducible protein-10 or IP-10) [1]. It is being investigated for its anti-inflammatory action in autoimmune conditions.
BLAST peptide sequence analysis reveals exact matches with heavy and light chain variable regions claimed in patent US8258266, and identify eldelumab as clone 6A5 [1].
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
9746 eldelumab
Synonyms Click here for help
BMS-936557 | MDX-1100
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 463
Other databases
GtoPdb PubChem SID 315661132
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