lumateperone

Ligand id: 9099

Name: lumateperone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 26.79
Molecular weight 393.22
XLogP 4.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
International Nonproprietary Names
INN number INN
10156 lumateperone
Synonyms
ITI-007
Comments
Lumateperone (ITI-007) is an investigational antipsychotic, with a novel mechanism of action, making it the first-in class agent of its type. In Phase 1 and Phase 2 clinical trials, lumateperone has demonstrated improved sleep maintenance, antipsychotic efficacy, and clinical signals consistent with reduction in negative symptoms associated with schizophrenia, depression and anxiety, and other symptoms associated with impaired social function.
Database Links
CAS Registry No. 313368-91-1 (source: WHO INN record)
ChEMBL Ligand CHEMBL3545045
DrugBank Ligand DB06077
GtoPdb PubChem SID 315661184
PubChem CID 9821941
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Wikipedia ITI-007