Compound class:
Synthetic organic
Comment: Neoceptin-3 is a synthetic molecular Toll-like receptor 4 (TLR4) agonist mimetic [2]. It bears no structural similarity with the endogenous ligand for TLR4, LPS, and in fact the biologically relevant molecular target for neoseptin-3 is the TLR4/MD-2 (LY96) complex [3]. This is one of the compounds claimed in patent WO2014131023 [1] in which the compound's action as an immune system adjuvant is claimed. Neoceptin-3 is claimed for its ability to elicit an immune response via TLR4, without the toxicity exhibited by LPS [3]. The S stereoisomer is specified in [3]. The R stereoisomer is represented by PubChem CID 90371379.
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Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
tert-butyl (2S)-2-[[4-amino-3-[2-(4-hydroxyphenyl)ethyl]benzoyl]amino]-4-phenylbutanoate |
Database Links ![]() |
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GtoPdb PubChem SID | 315661222 |
PubChem CID | 77461013 |
RCSB PDB Ligand | 61S, V2A |
Search Google for chemical match using the InChIKey | OACODUCFPHHCIH-SANMLTNESA-N |
Search Google for chemicals with the same backbone | OACODUCFPHHCIH |
UniChem Compound Search for chemical match using the InChIKey | OACODUCFPHHCIH-SANMLTNESA-N |
UniChem Connectivity Search for chemical match using the InChIKey | OACODUCFPHHCIH-SANMLTNESA-N |