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Compound class:
Endogenous peptide in human, mouse or rat
Comment: Rat PEN is one of the active fragments cleaved from pro-protein proSAAS. It is amino acids 221-242 of proSAAS. PEN appears to be involved in the regulation of feeding, possibly in concert with the BigLEN-GPR171 ligand-receptor system [1].
Species: Rat
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
Classification  |
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| Compound class | Endogenous peptide in human, mouse or rat |
| Gene/Precursor |
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| Database Links |
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| Specialist databases | |
| GPCRdb Ligand | PEN |
| Other databases | |
| Ensembl Gene | ENSRNOG00000046021 (Rn) |
| GtoPdb PubChem SID | 315661225 |
| UniProtKB | Q9QXU9 (Rn) |
