periciazine   

GtoPdb Ligand ID: 9216

Synonyms: pericyazine | propericiazine | RP-8909
periciazine is an approved drug (UK (2009))
Compound class: Synthetic organic
Comment: Periciazine is a phenothiazine antipsychotic. It has anti-dopaminergic, adrenolytic, anticholinergic, metabolic and endocrine effects.
2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 75.8
Molecular weight 365.16
XLogP 3.86
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES N#Cc1ccc2c(c1)N(CCCN1CCC(CC1)O)c1c(S2)cccc1
Isomeric SMILES N#Cc1ccc2c(c1)N(CCCN1CCC(CC1)O)c1c(S2)cccc1
InChI InChI=1S/C21H23N3OS/c22-15-16-6-7-21-19(14-16)24(18-4-1-2-5-20(18)26-21)11-3-10-23-12-8-17(25)9-13-23/h1-2,4-7,14,17,25H,3,8-13H2
InChI Key LUALIOATIOESLM-UHFFFAOYSA-N
Classification
Compound class Synthetic organic
Approved drug? Yes (UK (2009))
IUPAC Name
10-[3-(4-hydroxypiperidin-1-yl)propyl]phenothiazine-2-carbonitrile
International Nonproprietary Names
INN number INN
1398 periciazine
Synonyms
pericyazine | propericiazine | RP-8909
Database Links
ChEMBL Ligand CHEMBL251940
DrugCentral Ligand 2107
GtoPdb PubChem SID 315661292
PubChem CID 4747
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