risperidone

Ligand id: 96

Name: risperidone

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 64.16
Molecular weight 410.21
XLogP 3.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1993))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
Is prodrug? Yes
Active form paliperidone
IUPAC Name
3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[2,1-b]pyrimidin-4-one
International Nonproprietary Names
INN number INN
6085 risperidone
Synonyms
R-64-766 | R-64766 | Risperdal®
Comments
Risperidone is an atypical antipsychotic drug, functioning as a dopamine D2, serotonin 5-HT2 and α2-adrenoceptor antagonist.
Database Links
BindingDB Ligand 50001885
CAS Registry No. 106266-06-2
ChEBI CHEBI:8871
ChEMBL Ligand CHEMBL85
DrugBank Ligand DB00734
GtoPdb PubChem SID 135650903
PubChem CID 5073
RCSB PDB Ligand 8NU
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Search UniChem for chemical match using the InChIKey RAPZEAPATHNIPO-UHFFFAOYSA-N
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Wikipedia Risperidone

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Tocris
Risperidone
Cat. No. 2865