STK16-IN-1

Ligand id: 9692

Name: STK16-IN-1

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 50.16
Molecular weight 293.1
XLogP 4.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-(4-fluoro-3-methylphenyl)-7H-pyrrolo[2,3-h][1,6]naphthyridin-2-one
Comments
STK16-IN-1 is a selective inhibitor of serine/threonine kinase 16 (STK16) that can be used as a pharmacological tool to investigate the biological functions of STK16 [2]. It is compound 219 in a 2010 patent claiming mTOR inhibitors [1].
Database Links
GtoPdb PubChem SID 348353651
PubChem CID 58525066
Search Google for chemical match using the InChIKey WQNRDXHKVSKUPI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone WQNRDXHKVSKUPI
Search UniChem for chemical match using the InChIKey WQNRDXHKVSKUPI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone WQNRDXHKVSKUPI

Product suppliers

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Tocris
STK16-IN-1
Cat. No. 6036